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Collinsville, IL

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Moline, IL

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Sunrise Beach, MO

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Abingdon, MD

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Schaumburg, IL

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Mt Prospect, IL

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Terpene Profile: Caryophyllene

Known for its bold, spicy profile, strains with Caryophyllene (also known as Beta-Caryophyllene or β-Caryophyllene) offer more to the savvy consumer – they present a way to explore the subtle interplay between a plant’s scent and its influence on well-being. Join us in this guide as we navigate you through the world of caryophyllene dominant strains, their effects, and how to enjoy them.

What is a Terpene?

Terpenes are aromatic compounds that define the distinct flavors and scents of plants and some animals. In cannabis, terpenes like caryophyllene are not only responsible for the richness of the plant’s aroma but also contribute significantly to the effects that different strains produce.

Brush up on your cannabis terpene knowledge.


Black Pepper
Black pepper is one of the best examples of the spicy flavor and aroma associated with caryophyllene.

What is Caryophyllene?

Caryophyllene is a sesquiterpene very common in cannabis, as well as in black pepper, cloves, and cinnamon. Unlike other terpenes, caryophyllene binds directly to CB2 receptors in the endocannabinoid system, acting similarly to a cannabinoid, and may provide anti-inflammatory and analgesic effects. This unique quality distinguishes caryophyllene from other terpenes and adds to its therapeutic potential.

Curious about other terpenes? Learn about Bisabolol and Humulene.


Wedding Sherb a strain with caryophyllene in the grow room.
Wedding Sherb is one of the caryophyllene dominant strains in our library.

Caryophyllene in Cannabis

In the diverse world of cannabis, caryophyllene makes its presence known through the spicy, woody, and peppery notes it imparts. Strains with Caryophyllene are often sought after for their bold flavor profiles and potential gastrointestinal and anti-inflammatory benefits.

Effects and Benefits of Caryophyllene Terpene

Strains with Caryophyllene are not only chosen for their flavor but also for their potential therapeutic benefits. The terpene has been associated with reducing inflammation, pain relief, and even anxiety management. Its unique ability to interact with the endocannabinoid system allows it to offer a unique bouquet of benefits that can be especially appealing to medical cannabis users.

The Entourage Effect and Caryophyllene

The entourage effect describes the synergistic interaction where compounds in cannabis, including terpenes and cannabinoids, work together to enhance the overall effects. Beta-Caryophyllene is a significant player in this phenomenon. When combined with other cannabinoids, particularly CBD, it may amplify anti-inflammatory and pain-relieving properties, making caryophyllene dominant strains a popular choice for a comprehensive therapeutic regimen.

How to Identify Strains with Caryophyllene

Identifying caryophyllene dominant strains is key for consumers looking to harness its specific benefits. These strains typically possess a distinctively sharp, spicy scent that can remind one of black pepper or cloves.

Recognizing this scent can guide consumers towards making selections rich in caryophyllene. Lab-tested products from reputable companies will list dominant terpenes, helping you make informed decisions.

Caryophyllene Dominant Strains

Many strains contain this major terpene, caryophyllene dominant strains have a particularly high concentration that stands out in both aroma and effect. Some strains with caryophyllene in our catalog include:

A Bionic Cheetah Nug on white.
This strains spicy and earthy flavor profile indicates a strain with caryophyllene.

Bionic Cheetah

Bionic Cheetah is our take on Lit Farm’s cross of Cheetah Piss x Project 4516. An Indica-leaning hybrid (60 I / 40 S), she’s noted for compelling aesthetics, aroma, and soothing effects. Reach for Bionic Cheetah during your next evening session.

Reported Effects

Stress relief, Euphoria, Mood Elevation, Body Buzz, Pain Relief


Earthy, Spicy, Piney


Cheetah Piss x Project 4516

Top Terpenes

Beta-Caryophyllene, Limonene, Beta-Myrcene, Ocimene, Linalool.

Bred By

Lit Farms

Grown By

Revolution Cannabis

Shop Bionic Cheetah


REV DannyBoyOG Nug IHJ (1)
This strain is high in caryophyllene and delivers relief from pain

Danny Boy OG

True to its name, Danny Boy OG is an Indica-dominant hybrid, offering distinctive OG flavors of gas/diesel and rubber. Danny Boy OG delivers a soothing yet uplifting experience, elevating mood and combating discomfort – perfect for end-of-day pain relief.

Reported Effects

Pain and stress relief, mood elevation


Gas, Diesel, Rubber


Wedding Sherb x Cake Crasher

Top Terpenes

Beta-Caryophyllene, Beta-Myrcene, Limonene, Alpha-Humulene

Bred and Grown By

Revolution Cannabis

Shop Danny Boy OG

Georgia Pie, a caryophyllene dominant strain nug on a white background.
Is there a connection between pain relief and caryophyllene dominant strains?

Georgia Pie

Georgia Pie features a unique blend of aromas like sweet peaches, pie crust, candy, earth, and classic OG Kush. She’s a balanced hybrid that provides an energetic, euphoric high while also offering stress relief and pain-relieving properties.

Reported Effects

Euphoric, stress relief, energetic, body buzz, pain relief


Creamy, earthy, pie crust


Gelatti x Kush Mints

Top Terpenes

Beta-Caryophyllene, Limonene, Alpha-Humulene, Linalool, Alpha-Pinene

Bred By

Seed Junky Genetics

Grown By

Revolution Cannabis

Shop Georgia Pie

Final Thoughts

Beta-Caryophyllene is a major contributor to aromatic profiles and a possible cornerstone of cannabis’ therapeutic potential. Caryophyllene dominant strains offer a powerful example of how a single terpene can shape an experience, lending robust flavors and a suite of possible health benefits. The appreciation for the subtle yet significant role of terpenes like Beta-Caryophyllene in cannabis are only going to grow as we learn more.


Beta-caryophyllene is a dietary cannabinoid

Effects of super-class cannabis terpenes beta-caryophyllene

Everything You Need to Know About Caryophyllene

General Cannabis FAQ

Cannabis, often referred to as marijuana, is a plant that has been used for thousands of years for various purposes, including medicine, textiles, and recreation. The plant contains compounds known as cannabinoids, with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) being the most well-known. THC is primarily responsible for the plant’s psychoactive effects, while CBD is recognized for its potential therapeutic benefits without causing a “high.”

Many countries and U.S. states have decriminalized or legalized the use of marijuana for medical use, recreational, or both. The legal status changes frequently as legislation evolves.

In the U.S., states vote to regulate marijuana use on an individual basis. While it remains illegal at the federal level, numerous states have legalized it for medicinal and/or recreational use.

The following states have legalized medical, recreational, or both:

  • Alaska – Medical
  • Arizona – Legal
  • Arkansas – Medical
  • California – Legal
  • Colorado – Legal
  • Connecticut – Legal
  • Delaware – Legal
  • District of Columbia – Legal
  • Florida – Medical
  • Hawaii – Medical (Possession decriminalized for small amounts)
  • Illinois – Legal
  • Louisiana – Medical (Possession decriminalized for small amounts)
  • Maine – Legal
  • Maryland – Legal
  • Massachusetts – Legal
  • Michigan – Legal
  • Minnesota – Legal
  • Mississippi – Medical (Possession decriminalized for small amounts)
  • Missouri – Legal
  • Montana – Legal
  • Nevada – Legal
  • New Hampshire – Medical (Possession decriminalized for small amounts)
  • New Jersey – Legal
  • New Mexico – Legal
  • New York – Legal
  • North Dakota – Medical (Possession decriminalized for small amounts)
  • Ohio – Medical (Possession decriminalized)
  • Oklahoma – Medical
  • Oregon – Legal
  • Pennsylvania – Medical
  • Rhode Island – Legal
  • South Dakota – Medical
  • Utah – Medical
  • Vermont – Legal
  • Virginia – Legal
  • Washington – Legal
  • West Virginia – Medical


Outside of the U.S., countries like The Netherlands, Canada, and, more recently, Thailand have legalized cannabis on a national level.

Always check local laws and regulations in your specific location.

In states where marijuana has been legalized, you can purchase products at licensed dispensaries. Revolution products are available at Enlightened, Revolution, and partner dispensaries in Illinois, Arkansas, Missouri, and Maryland. Find a dispensary near you.

Keep in mind that dispensaries may cater to medical patients, recreational consumers, or both, depending on local laws.

Always ensure that you are buying from a reputable and licensed establishment to guarantee product quality and safety.

The effects of cannabis vary widely depending on the strain, dosage, method of consumption, an individual’s endocannabinoid system, and more.

Some commonly reported effects include:

Psychoactive Effects: Euphoria, mood elevation, cerebral stimulation, stress relief, calming effects, and relaxation.

Physical Effects: Pain relief, body buzz, anti-inflammation, anti-nausea, energy boost or sedation, and appetite stimulation

*Medical Benefits: Cannabis is believed to have a range of therapeutic effects and alleviation of symptoms related to conditions like epilepsy, PTSD, and more.

*Marijuana is not approved by the FDA to treat, cure, or prevent any disease.

The primary difference lies in their intended use:

Medical Cannabis: Used as a treatment and alleviation of symptoms for specific health conditions. Medical strains might be cultivated and processed to have higher CBD content or other therapeutic compounds. Medical cannabis requires a physician who usually prescribes or recommends it as a treatment option.

Recreational Cannabis: Used without a medical justification but for personal enjoyment and fulfillment.

The process varies from state to state but typically involves the following steps:

Doctor’s Recommendation: Schedule an appointment with a physician who is authorized to recommend medical marijuana. Discuss your health conditions and reasons for seeking cannabis as a treatment.

Application: Once you have a doctor’s recommendation, you’ll usually need to apply for a medical marijuana card through a designated state or country agency.

Proof & Identification: Provide necessary identification and proof of residency as required by your jurisdiction.

Fee Payment: Most jurisdictions require a fee for the application and issuance of a medical marijuana card.

Card Issuance: Once approved, you will receive your medical marijuana card, allowing you to purchase cannabis at designated medical dispensaries.

If you’d like more detailed information, please read our state-specific medical card guide here.